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New dye technique may help surgeons spot hidden cancer spread

NCT ID NCT05191212

Knowledge-focused Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a modified method for injecting a green dye (indocyanine green) to help surgeons see lymph nodes during robotic surgery for early-stage endometrial cancer. The new approach injects the dye until the lymphatic channels are visible in real time, aiming to improve detection of sentinel lymph nodes on both sides of the pelvis. The trial enrolled 80 patients and compared this technique with the standard injection method.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
indocyanine green (ICG)
What this could lead to
If the modified technique proves better, it could improve the accuracy of sentinel lymph node detection during surgery for early-stage endometrial cancer.
What could go wrong
This is a small, single-center study with 80 participants, so results may not apply broadly. The intervention is a procedural variation, not a new drug or cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Jul 2021

Finished

Sep 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients with clinical stage 1-2 endometrial cancer ASA 1-3 patients. Ability to provide written informed consent Exclusion Criteria: Patients with clinical stage 3-4 endometrial cancer Patients who are not suitable for robotic surgery due to their comorbidities (such as glaucoma, COPD, asthma) ASA 4-5 patients. Patients unable or unwilling to provide informed consent

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrium neoplasm uterine cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometrial cancer Endometrial neoplasms Sentinel lymph node biopsy (SLNB)

Contacts and locations

Locations

  • Gökhan Demirayak

    Istanbul, 34147, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.