New therapy aims to retrain the brain to stop seizures in teens
NCT ID NCT05819268
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a behavioral therapy called ReACT for teens aged 11-18 with functional seizures (non-epileptic). The therapy involves 12 sessions with a therapist to help manage seizures. Researchers want to see if a larger study is possible by checking how many teens join, stick with treatment, and find it acceptable. Participants are randomly assigned to ReACT or another online therapy (CATCH-IT).
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Retraining and Control Therapy (ReACT) – a behavioral therapy
- What this could lead to
- If this therapy works, it could provide a non-drug way to help teens reduce or stop functional seizures.
- What could go wrong
- This is a small feasibility study, not a full test of effectiveness. The therapy may not work for everyone, and some teens might not stick with it.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 108 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Mar 2024
- Expected to finish
-
Aug 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
11 to 18 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Males and females ages 11-18 * Diagnosis of functional seizures * Internet access for telehealth sessions and CATCH-IT Exclusion Criteria: * Comorbid epilepsy * Less than 4 functional seizures per month * Other paroxysmal nonepileptic events (e.g. hypoxic-ischemic phenomena, sleep disorders or migraine-associated disorders) * Participation in other therapy * Severe intellectual disability * Severe mental illness (active delusions/hallucinations)
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Convulsion, non-epileptic are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can retraining your brain stop seizures? new study tests ReACT therapy
- New study aims to map out best treatments for FND
- New therapy aims to retrain the brain to stop fake seizures
- Could a 3-Day TMS course ease functional seizures?
- New therapy aims to retrain the brain in kids with Seizure-Like episodes