Could a single dose of radiation before surgery replace weeks of treatment?

NCT ID NCT06444269

Recruiting now Disease control Sponsor: University of Texas Southwestern Medical Center Source: ClinicalTrials.gov ↗

First seen Nov 05, 2025 · Last updated Jun 13, 2026 · Updated 27 times

Summary

This study tests a new way to treat early-stage ER+ breast cancer using a single, strong dose of radiation before surgery. It also explores using a special ultrasound with microbubbles to check lymph nodes without a surgical biopsy. The goal is to see if this approach can eliminate the tumor and simplify treatment, while still requiring surgery if needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

UT Southwestern Medical Center-Dallas
RECRUITING

Dallas, Texas, 75390, United States

Contact Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER