New study tests bronchoscopy + CT for faster pneumonia diagnosis
NCT ID NCT07308340
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether using a bronchoscopy (a camera in the airways) together with a CT scan can more accurately identify the germs causing severe pneumonia than a CT scan alone. Researchers will review data from 400 patients to compare the two methods. The goal is to help doctors diagnose and treat severe pneumonia faster.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to faster and more accurate diagnosis of severe pneumonia, helping doctors choose the right treatment sooner.
- What could go wrong
- This is a retrospective study, not a controlled trial, so results may be less reliable. The combination method may not improve accuracy enough to change practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
May 2026
An estimate. Start dates often move.
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population includes adult patients (≥18 years old) admitted to the study institution between January 2024 and December 2025, with a confirmed diagnosis of severe pneumonia (per Chinese clinical guidelines for community-acquired or hospital-acquired pneumonia). All included patients must have undergone both standalone lung CT and bronchoscopic imaging (CT-guided) during hospitalization, with complete imaging records. They also need to have completed at least one microbial gold standard test (e.g., pathogen culture, nucleic acid detection) with available reports, and intact electronic medical records (demographics, treatment, prognosis). Patients are excluded if they have incomplete imaging/microbial data, bronchoscopy for non-diagnostic purposes, duplicate admissions, or are under 18 years old.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients admitted to the study institution between January 2024 and December 2025, with a clinical diagnosis of severe pneumonia (consistent with the diagnostic criteria of the Chinese Guidelines for the Diagnosis and Treatment of Community-Acquired Pneumonia. * Patients who underwent both standalone lung CT examination and bronchoscopic imaging examination during hospitalization; complete imaging reports and bronchoscopy operation records are available. * Patients who completed at least one type of microbial standard test (as defined in Primary Outcome Measure: e.g., pathogen culture, nucleic acid detection, GM test); complete test reports are available. * Medical Records: Complete electronic medical records are available, including demographic information (age, gender), clinical symptoms, treatment regimens, and prognosis data (length of hospital stay, in-hospital mortality). Exclusion Criteria: * Imaging/Microbial Data Deficiency: Patients with incomplete imaging data (e.g., missing lung CT images, unrecorded bronchoscopic mucosal changes) or unavailable microbial gold standard test results. * Bronchoscopy Contraindications: Patients who underwent bronchoscopic imaging for non-diagnostic purposes (e.g., foreign body removal, hemostasis) or had bronchoscopy-related complications (e.g., severe hemorrhage, pneumothorax) that affected examination completion. * Duplicate Enrollment: Patients who were admitted multiple times for severe pneumonia during the study period; only the first admission is included to avoid duplicate data.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Severe pneumonia are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which sedation approach helps pneumonia patients breathe on their own sooner?
- Protein power: could a High-Protein diet get pneumonia patients off ventilators faster?
- Playful breathing exercises may speed recovery for kids with pneumonia
- Massive study aims to unlock Pneumonia's secrets
- Massive data dive aims to tame sepsis in kids
- AI could revolutionize severe pneumonia diagnosis