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Protein power: could a High-Protein diet get pneumonia patients off ventilators faster?

NCT ID NCT07634328

Knowledge-focused Sponsor: Fayoum University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a high-protein diet helps patients on breathing machines with severe pneumonia recover faster. Researchers will compare patients getting a high-protein diet to those on a standard-protein diet, tracking how long they need the ventilator and whether they regain muscle strength. The goal is to see if better nutrition can improve outcomes for these critically ill patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-protein diet
What this could lead to
If it works, this could point toward better nutrition guidelines for critically ill patients to speed recovery and reduce time on a ventilator.
What could go wrong
This is a small observational study, not a randomized trial, so results may be influenced by other factors. It cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

mechanically ventilated patients with severe pneumonia

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years. * Mechanically ventilated patients with severe pneumonia. * Expected ICU stay ≥ 72 hours. Exclusion Criteria: * Patients who died before 72 hours of ICU admission. * Chronic liver failure or decompensated cirrhosis. * End-stage renal disease (CKD stage 5 or dialysis dependent). * Neuromuscular diseases or pre-existing severe muscle wasting. * Pregnancy. * Patients with pre-existing malnutrition (e.g., BMI \<18.5 kg/m² ). * Contraindications to enteral feeding, such as: 1. Mechanical bowel obstruction. 2. Severe gastrointestinal bleeding. 3. High-output fistulas involving the gastrointestinal tract. 4. Recent gastrointestinal surgery preventing enteral access.

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Conditions

The condition(s) this trial relates to.

pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mechanically ventilated patients Severe pneumonia

Contacts and locations

Locations

  • Faculty of medicine Fayoum university

    Al Fayyum, Faiyum Governorate, 63514, Egypt

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