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Could one hour replace two days? new trial aims to speed up cancer care

NCT ID NCT06965101

Symptom relief Sponsor: The Christie NHS Foundation Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using an MRI machine to guide radiotherapy can treat metastatic spinal cord compression in a single one-hour appointment, instead of the usual two visits (a planning CT scan then radiotherapy). About 72 adults with confirmed spinal cord compression will be split into two groups: one gets the new one-stop MRI-guided treatment, the other gets standard care. Researchers will check if the new method is faster, more convenient, and still delivers the full radiation dose as planned.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Radiotherapy (8 Gray single fraction delivered via MRI-guided linear accelerator)
What this could lead to
If successful, this could make treatment for spinal cord compression faster and more convenient by cutting it from two appointments to one.
What could go wrong
This is a small, early-stage feasibility study (72 participants) focused on logistics, not on whether the treatment works better. The MRI-guided approach may not be practical for all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Nov 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Confirmed Diagnosis of MSCC * Referred for an 8Gy, Single Fraction of Radiotherapy * 18 years or older. * Able to give informed consent in writing or verbally. * Willing to complete patient experience questionnaire * Willing to have the research team review their case notes for up to 1 year following Exclusion Criteria: * Participant does not have capacity and cannot give informed consent. * Any evidence of significant clinical disorder or laboratory finding which, in the opinion of the investigator, make it undesirable for the patient to participate in the study. * Participant is unwilling to allow researchers to access their clinical notes and diagnostic scans. * Participant is unwilling to complete an experience questionnaire * The participant cannot speak or understand English. Exclusion Criteria MRL arm: * Any contraindications to MRI identified after MRI safety screening * Unable to tolerate MRI scanning * Uncontrolled pain/ poor pain control. * MSCC in the cervical spine. * More than one vertebral level of compression

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm in the spinal cord Spinal Cord Compression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Metastatic spinal cord compression

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, M20 4BX, United Kingdom

More trials for these conditions

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