Speedy gene test aims to give answers on birth defects in just 7 days

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pregnancies (17 - 34 weeks of gestation (WG)) with US anomalies namely either i) two major anomalies, ii) one major and one minor anomalies, or iii) one anomaly (major or minor) with a strong suspicion of genetic cause (such as corpus callosum anomaly); * Couples for whom an etiological diagnosis could modify the pregnancy outcome and/or the pre and/or postnatal management; * Pregnant women who receive invasive prenatal sampling for ES+CMA; * Sufficient quantity of amniotic fluid to collect an additional sample for GS; * Possibility of blood samples from the pregnant woman and the biological father; * Written consent for genetic analysis from pregnant woman and biological father of foetus; * Provision of signed and dated of both parents' consent form for the study. For the exploratory qualitative objective/endpoint: \- A least one member of the couple willing to accept 2 telephone or video consultations, and able to speak and understand French. Exclusion Criteria: * Refusal of the pregnant woman or biological father to participate in the study; or refusal to collect blood samples from one or both parents; * Pregnancy before 17 WG or after 34 WG (to limit the risk of reporting results after birth); * Isolated increase nuchal translucency on ultrasound; * Couples for whom an etiological diagnosis would not modify the pregnancy outcome; * Pregnant woman and biological father not affiliated to a social security system or not beneficiaries of such a system; * Pregnant woman and/or biological father who are protected and unable to understand the protocol and express their consent; * Pregnant women and/or biological fathers under legal protection (guardianship, tutorship) or to a court order For the exploratory qualitative objective/endpoint: \- The two members of the couple unable to carry out two one-hour telephone interviews in French.