AI scans 3000 liver cancer patients to pick best therapy
NCT ID NCT07368530
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study analyzed medical images and data from 3000 patients with advanced liver cancer that cannot be removed by surgery. Researchers used an AI technique called radiomics to see if they could identify which patients would respond better to one of two standard treatments: TACE (a procedure that blocks the tumor's blood supply) or HAIC (chemotherapy delivered directly to the liver). The goal is to develop a tool that helps doctors personalize treatment decisions, but because this is a retrospective study looking at past data, it cannot prove that the AI model will work for future patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors choose the best liver cancer treatment for each patient, improving outcomes without a one-size-fits-all approach.
- What could go wrong
- This is a retrospective study, meaning it looks back at old data, so it cannot prove cause and effect. The AI model may not work as well in new patients or other hospitals.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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3,000 people
The number who actually took part.
- Started
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Jan 2015
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with unresectable HCC who TACE or HAIC
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients diagnosed with hepatocellular carcinoma (HCC) based on clinical or pathological criteria; 2. Barcelona Clinic Liver Cancer (BCLC) stage B or C, assessed as unresectable by surgical evaluation; 3. Received either TACE or HAIC as the sole interventional treatment modality throughout the treatment course (no crossover between the two modalities allowed); 4. Liver function classified as Child-Pugh Class A or B, or achieved this standard after medical treatment; 5. Performance status (PS) score of 0 or 1. Exclusion Criteria: 1. Patients with an unclear diagnosis or those with concurrent other malignant tumors; 2. Liver function classified as Child-Pugh Class C or worse, which cannot be improved after hepatoprotective treatment; 3. Patients with severe infections, such as respiratory, biliary tract, or abdominal infections; 4. Patients with severe underlying diseases, particularly immune-related disorders. 5. Patients with severely incomplete or missing baseline or outcome data.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Affiiated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, 510080, China
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Other studies related to the condition(s) this trial covers.
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