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New hope for chronic knee pain after replacement? radiofrequency ablation trial launches

NCT ID NCT05920382

Symptom relief Sponsor: Consorci Sanitari de l'Alt Penedès i Garraf Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a procedure called radiofrequency ablation can reduce chronic pain in people who still have knee pain after knee replacement surgery. The treatment uses heat to target specific nerves around the knee that may be causing pain. About 86 adults with persistent knee pain for at least 6 months after surgery will be randomly assigned to receive either the real treatment or a placebo, and researchers will measure changes in pain and function after 3 months.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 86 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2023

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals who have undergone knee arthroplasty. * Chronic knee pain post-knee arthroplasty for at least 6 months after the procedure and less than 5 years. * Pain intensity on the numerical visual scale ≥ 5 out of 10 points. * Stable pain for the last 30 days. * The knee is the location with the highest intensity of pain, in the case of patients with multiple joint pains. Exclusion Criteria: * Acute knee pain. * Psychiatric illness or dementia that may interfere with or hinder study assessments. * Diagnosis of fibromyalgia, chronic fatigue syndrome, or central sensitization syndrome. * Knee infiltration with corticosteroids in the past 30 days. * Changes in oral analgesic medication in the past 30 days.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic knee pain Chronic post operative pain Chronic post-surgical pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Consorci Sanitari Alt'Pènedes i Garraf

    RECRUITING

    Barcelona, Catalonia, 08810, Spain

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