CHRONIC KNEE PAIN

This study tests a procedure called radiofrequency ablation to treat chronic knee pain after knee replacement surgery. The treatment uses heat to target specific nerves around the knee that may be causing pain. Researchers will compare the real treatment to a placebo in 86 adults…

This study tests a 4-week program that teaches people with chronic muscle or joint pain how to use ear acupressure on themselves, with help from a smartphone app. About 693 adults from rural areas will be split into three groups: one with app-based training, one with in-person tr…

This study tests if a new nerve stimulation treatment, alone or with a steroid injection, can improve knee movement and reduce pain better than the standard steroid injection alone. About 45 adults with long-term knee pain will take part. The goal is to find a safer, more effecti…

This study tests a device that uses focused sound waves to block pain signals in the knee, without needles or surgery. Ten adults with moderate to severe knee osteoarthritis will receive a one-hour treatment and be followed for six months. The goal is to see if the device is safe…

This study looks at how long-term pain from knee problems or fibromyalgia changes the way nerves talk to muscles. Researchers will test pain sensitivity, muscle activity, and physical function in 135 adults aged 40 and older, including healthy volunteers. The goal is to better un…

This observational study looks at why some people with knee osteoarthritis feel more pain than others, even when their knee damage looks similar. About 300 adults aged 45-80 with chronic knee pain will complete surveys, walking tests, knee X-rays and MRIs, brain scans, and sensor…