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New combo therapy for breast cancer shows promise in early trial

NCT ID NCT06139107

First seen Nov 15, 2025 · Last updated May 22, 2026 · Updated 24 times

Summary

This early-phase study is testing whether giving radiation therapy along with two targeted drugs (abemaciclib and letrozole) before surgery is safe for people with a common type of early-stage breast cancer (HR+/HER2-). The study involves 15 participants and focuses on side effects and how well the treatment is tolerated. The goal is to gather information for future, larger studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cooperman Barnabas Medical Center

    RECRUITING

    Livingston, New Jersey, 07039, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • RWJBarnabas Health - Robert Wood Johnson University Hospital Somerset

    RECRUITING

    Somerville, New Jersey, 08873, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • RWJBarnabas Health Clara Maas Medical Center

    RECRUITING

    Belleville, New Jersey, 07109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rutgers Cancer Institute of New Jersey

    RECRUITING

    New Brunswick, New Jersey, 08903, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.