New combo therapy for breast cancer shows promise in early trial
NCT ID NCT06139107
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study is testing whether giving radiation therapy together with two drugs (abemaciclib and letrozole) before surgery is safe and doable for people with a common type of early-stage breast cancer (HR+/HER2-). About 15 participants will receive this combination to see how well they tolerate it and to gather initial information on its effects. The goal is to find better ways to treat breast cancer before surgery, potentially improving outcomes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cooperman Barnabas Medical Center
RECRUITINGLivingston, New Jersey, 07039, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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RWJBarnabas Health - Robert Wood Johnson University Hospital Somerset
RECRUITINGSomerville, New Jersey, 08873, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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RWJBarnabas Health Clara Maas Medical Center
RECRUITINGBelleville, New Jersey, 07109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rutgers Cancer Institute of New Jersey
RECRUITINGNew Brunswick, New Jersey, 08903, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••