Antioxidant MitoQ tested for boosting cold tolerance in black individuals

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female, age 18-40 * In good health as determined by OMSO (Office of Medical Support and Oversight) * Willing to refrain from exercise and caffeinated or alcoholic beverages for 12 hours before each testing session * Willing to refrain from antioxidant-rich foods, such as blueberries, pecans, and dark chocolate, 48 h before each testing session * Eumenorrheic females (menstrual cycle length between 24-35 days) or females taking oral contraceptives, or utilizing implantable contraception (e.g., intrauterine device) * Have supervisor approval if active-duty military or a federal employee at NSSC Exclusion Criteria: * History of cold injuries of any severity (e.g., frostbite, trench foot, chilblains) * Raynaud's syndrome * Cold-induced asthma/bronchospasm * Previous hand/finger injuries that impair dexterity and hand function * Metal hardware (plates/screws) in the forearms and hands * Smoke, vape, or use smokeless tobacco or other nicotine-containing products habitually (unless have quit \> 4 months prior) * Current use of medications (except for birth control) or dietary supplements that could alter cardiovascular, thermoregulatory, or vascular control (e.g., anti-hypertensives, statins) * History of disease of the gastrointestinal tract including (but not limited to) diverticulosis, diverticulitis and inflammatory bowel disease, peptic ulcer disease, Crohn's disease, ulcerative colitis; or previous gastrointestinal surgery * Have a history of renal disease including (but not limited to) chronic kidney disease, acute kidney injury, kidney stone disease, glomerular disease, or nephritis * Known allergies to medical adhesives * Known allergy to MitoQ * Difficulty swallowing pills * Heart, lung, kidney, muscle, or nerve disorder(s) * A planned MRI during the study or within 3 days after completing a cold test * Women who are pregnant, planning to become pregnant, or breastfeeding * Not willing to have small areas of skin on the body shaved (if deemed necessary for attachment of study instrumentation) * Have donated blood within 8 weeks of the study or plan to donate blood during the study * Lesions on a significant portion of the upper extremities due to skin pigmentation disorders (e.g., vitiligo, psoriasis)