New combo therapy aims to keep follicular lymphoma in check longer
NCT ID NCT02390869
First seen Dec 08, 2025 · Last updated May 23, 2026 · Updated 25 times
Summary
This study looks at whether adding lenalidomide to the standard drug rituximab (called R2) can help keep follicular lymphoma from coming back longer than rituximab alone. It involves 128 adults whose lymphoma returned after previous treatment and who cannot have a stem cell transplant. Participants receive either R2 or rituximab alone as maintenance therapy after initial chemoimmunotherapy, and researchers track how long they stay cancer-free and any side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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A O Papardo
Messina, Italy
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A.O. S. Maria di Terni
Terni, TR, 05100, Italy
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A.O. Universitaria Careggi Di Firenze
Florence, 50139, Italy
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A.O. Universitaria Citta' Della Salute E Della Scienza Di Torino
Torino, 10126, Italy
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A.O. Universitaria Ospedale Vittorio Emanuele E Ferrarotto Di Catania
Catania, 95124, Italy
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A.O. Universitaria Policlinico Di Modena
Modena, 41124, Italy
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A.O.U. Citta della Salute e della Scienza di Torino - Ematologia Universitaria
Torino, Italy
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A.S.L. 9 Opsedali Riuniti del Canavese
Ivrea, Italy
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AO Arcispedale S.Maria Nuova Ematologia
Reggio Emilia, Italy
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AO Santa Croce e Carle
Cuneo, 12100, Italy
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AOU La Sapienza
Roma, 00161, Italy
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AOU Maggiore della Carità di Novara
Novara, 28100, Italy
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ASST Grande Ospedale Metropolitano Niguarda
Milan, MI, 20162, Italy
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ASST Valle Olona - Ospedale di Circolo di Busto Arsizio
Busto Arsizio, Varese, Italy
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AUSL di Ravenna
Ravenna, RA, 48100, Italy
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Area Vasta Romagna e IRST
Meldola (FC), Italy
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Ausl Di Piacenza
Piacenza, 29121, Italy
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Centro di riferimento Oncologico - Oncologia Medica A
Aviano (PN), Italy
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Divisione di Ematologia Spedali Civili
Brescia, Italy
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Ematologia - OSPEDALE DI CIRCOLO E FONDAZIONE MACCHI
Varese, 21100, Italy
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Fondazione Del Piemonte Per L'Oncologia Ircc Di Candiolo
Candiolo, Torino, 10060, Italy
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Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Italy
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IRCCS Istituto Oncologico Veneto -Oncologia 1
Padova, Italy
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Nuovo Ospedale Civile di Sassuolo - Day Hospital Oncologico
Sassuolo, Italy
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Ospedale C. e G. Mazzoni UOS Ematologia
Ascoli Piceno, Italy
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Ospedale S. Giacomo di Castelfranco Veneto
Castelfranco Veneto, Treviso, 31033, Italy
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Ospedale SS Antonio Biagio e Cesare Arrigo
Alessandria, Italy
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SOS Ematologia Divisione Medicina Interna Ospedale degli Infermi
Biella, Italy
Conditions
Explore the condition pages connected to this study.