HIV Patients' CAR T-Cell cancer treatment under the microscope
NCT ID NCT05784415
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked back at 30 people with HIV who received a special cancer treatment called CAR T-cell therapy for certain blood cancers. Researchers collected information from medical records to see what side effects occurred and how the immune system changed over time. The goal was to learn more about how this therapy works in people living with HIV.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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30 people
The number who actually took part.
- Started
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May 2021
- Finished
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Nov 2024
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
People living with HIV treated with CD19-directed CAR T cell therapy for B-cell lymphoid malignancies
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Documented history of HIV infection * Received CD19-directed CAR T cell therapy for acute lymphoblastic leukemia, diffuse large B-cell lymphoma, high-grade B-cell lymphoma, transformed follicular lymphoma, or primary mediastinal B-cell lymphoma * Age ≥ 18 years Exclusion Criteria: • Prior treatment with any CAR T cell therapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Pennsylvania Hospital
Philadelphia, Pennsylvania, 19106, United States
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Other studies related to the condition(s) this trial covers.
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