New combo aims to stop lymphoma from spreading to the brain
NCT ID NCT05257018
First seen Apr 02, 2026 · Last updated Jun 18, 2026 · Updated 10 times
Summary
This study tests a chemotherapy regimen (R-CDOP) plus a drug injected into the spine (intrathecal methotrexate) in 83 adults with untreated diffuse large B-cell lymphoma at high risk of spreading to the brain. The goal is to see if this combination lowers the chance of central nervous system relapse within two years. Participants must be 18-75 and have specific high-risk features.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Cancer Hospital affilicaited to Xinjiang Medical University
NOT_YET_RECRUITINGÜrümqi, Xinjiang, China
Contact
Contact
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Dongmei Ji
RECRUITINGShanghai, Shanghai Municipality, 021, China
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.