New combo aims to stop lymphoma from spreading to the brain

NCT ID NCT05257018

First seen Apr 02, 2026 · Last updated May 01, 2026 · Updated 4 times

Summary

This study tests a chemotherapy regimen (R-CDOP) plus a drug injected into the spine (intrathecal methotrexate) in 83 adults with untreated diffuse large B-cell lymphoma who have a high risk of the cancer spreading to the central nervous system. The goal is to see if this combination lowers the chance of brain relapse within two years. Participants must be between 18 and 75 years old and have not received prior treatment.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Cancer Hospital affilicaited to Xinjiang Medical University

    NOT_YET_RECRUITING

    Ürümqi, Xinjiang, China

    Contact

    Contact

  • Dongmei Ji

    RECRUITING

    Shanghai, Shanghai Municipality, 021, China

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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