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Engineered immune cells injected into the brain take on childhood cancers

NCT ID NCT05768880

First seen Nov 20, 2025 · Last updated May 22, 2026 · Updated 28 times

Summary

This early-stage study tests a new treatment for children and young adults with certain hard-to-treat brain tumors, including DIPG and DMG. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack tumor cells, then delivered directly into the fluid-filled spaces of the brain. The main goals are to see if this approach is safe and to find the best dose for future studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

Conditions

Explore the condition pages connected to this study.