Could a pyramid-shaped workout help smokers breathe easier?
NCT ID NCT07765485
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This trial tests whether a specific type of treadmill exercise, called pyramidal aerobic training, can improve breathing in young adult male smokers with mild to moderate lung impairment. Participants will exercise three times a week for eight weeks, with intensity varying in a pyramid pattern. The study measures lung function, exercise capacity, and quality of life to see if this training offers benefits.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Pyramidal aerobic training on a treadmill, three times weekly for eight weeks
- What this could lead to
- If effective, this exercise program could offer a simple, drug-free way to improve lung function and quality of life in smokers.
- What could go wrong
- This is a small, early-stage trial, so results may not apply broadly. Exercise may not reverse smoking-related lung damage, and benefits could be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 28 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Cigarette smoker males aged from 18 to 28 years. * Smoking index = 50. * Sedentary lifestyle. * BMI between 18.5 and 29.9 kg/m². * Cigarette smokers demonstrate mild to moderate impairment in ventilatory function confirmed by baseline spirometry. * SASEQ (Smoking Abstinence Self-Efficacy Questionnaire) moderate self-efficacy, score from 9 to 16. * Cigarette smokers are able and willing to participate in aerobic training sessions Exclusion Criteria: * Patients diagnosed with chronic respiratory diseases such as asthma. * Patients with cardiovascular diseases or other systemic illnesses that contraindicate exercise. * Patients who experienced recent respiratory infections within the last 4 weeks. * Patients currently engaged in regular structured aerobic or respiratory training programs.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Physical Therapy, Ahram Canadian University
Giza, October City, Egypt
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