Pulse wave test may replace needles to check nerve block success
NCT ID NCT07669688
First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times
Summary
This study looks at whether a non-invasive measurement called pulse wave transit time (PWTT) can detect when a nerve block has taken effect. Researchers will monitor 25 patients having hand surgery under an infraclavicular block. PWTT and other vital signs will be recorded before and after the block to see if changes in blood vessel tone reliably indicate successful sympathetic blockade.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could provide a simple, non-invasive way to confirm that a nerve block is working during surgery.
- What could go wrong
- This is a very small, early observational study with only 25 participants. It is not testing a treatment, so it cannot lead to a cure or therapy on its own.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 25 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of adult patients aged 18-65 years with ASA physical status I who are scheduled to undergo elective upper extremity hand surgery under ultrasound-guided infraclavicular brachial plexus block. All participants will receive standard-of-care anesthesia management. Patients with contraindications to peripheral nerve block, significant systemic disease, obesity (BMI ≥30 kg/m²), coagulation disorders, opioid use, or conditions affecting sympathetic activity will be excluded. Only patients who provide informed consent will be enrolled.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients undergoing elective upper extremity hand surgery * 18 - 65 years * ASA I * No coagulopathy, thrombocytopenia, coagulation disorders * Patients who provide informed consent to participate in the study Exclusion Criteria: * History of drug allergy relevant to study procedures or local anesthetics * Body mass index (BMI) ≥ 30 kg/m² * Body weight \< 40 kg * Age \< 18 years or \> 65 years * History of significant cardiac disease (e.g., arrhythmia, conduction abnormalities) * Coagulopathy (INR \> 1.5 or platelet count \< 100,000/mm³) * Pregnancy or lactation * Infection at the site of peripheral nerve block * ASA II-IV * Failed block or motor block duration exceeding 30 minutes * Patients reporting pain (NRS ≥ 3), due to potential influence on sympathetic activity * Chronic opioid use
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sakarya University-Anesthesiology and Reanimation Department
Sakarya, Turkey (Türkiye)
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