Sugar water vs. salt water: which makes pain blocks last longer?
NCT ID NCT07386327
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways to dilute the numbing drug bupivacaine for a nerve block used during arm surgery. Researchers want to see if using sugar water (5% dextrose) instead of salt water (0.9% saline) affects how well and how long the block works. About 90 adults having elective upper arm surgery will take part.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine diluted with 5% dextrose or 0.9% saline
- What this could lead to
- If successful, this could show that using dextrose as a diluent improves pain relief after arm surgery.
- What could go wrong
- This is a small, early-stage study. The results may not apply to all patients or surgeries, and the effect may be minimal.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients who agree to participate in the study and provide written informed consent * Patients scheduled for elective upper extremity surgery for whom infraclavicular block is considered appropriate for anesthetic management * Age between 18 and 65 years * American Society of Anesthesiologists (ASA) physical status I-III * Patients with a normal neurological examination in the extremity scheduled for peripheral nerve block Exclusion Criteria: * Patients who decline to participate in the study or refuse to provide informed consent * History of allergy or hypersensitivity to study medications * Body mass index (BMI) ≥ 30 kg/m² * Body weight less than 40 kg * Age below 18 years or above 65 years * History of significant cardiac disease (e.g., arrhythmia, conduction disorders) * Presence of coagulopathy (international normalized ratio \[INR\] \> 1.5 and/or platelet count \< 100,000/mm³) * Hepatic failure or significant liver dysfunction * Pregnant patients * Infection at the planned peripheral block site * Presence of neurological deficit in the extremity planned for peripheral nerve block * Patients with uncontrolled diabetes mellitus and/or established diabetic neuropathy * American Society of Anesthesiologists (ASA) physical status IV
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sakarya University-Anesthesiology and Reanimation Department
RECRUITINGSakarya, 54100, Turkey (Türkiye)
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