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Can exercise change COPD inflammation? new study investigates

NCT ID NCT07376161

Knowledge-focused Sponsor: Esra Yazar Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a structured exercise and education program (pulmonary rehabilitation) can reduce inflammation and oxidative stress in people with stable COPD. Researchers will measure specific blood markers before and after the program in 27 adults aged 40-80. The goal is to understand if this therapy has biological effects beyond just improving symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 27 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients aged 40 to 80 years with a diagnosis of stable COPD, defined according to the GOLD criteria (FEV₁/FVC \< 70% and FEV₁ \< 70% predicted), who are former smokers with a smoking history of at least 10 pack-years, and who are referred to the pulmonary rehabilitation program of our institution, will be consecutively enrolled in the study.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 40-80 years with a diagnosis of stable COPD * Airflow limitation defined according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria (forced expiratory volume in 1 second / forced vital capacity \[FEV₁/FVC\] \< 70% and forced expiratory volume in 1 second \[FEV₁\] \< 70% predicted) * Former smokers with a smoking history of at least 10 pack-years * Clinically stable disease at the time of enrollment * Ability and willingness to participate in the pulmonary rehabilitation program * Provision of written informed consent Exclusion Criteria: * Current smokers * History of acute COPD exacerbation or respiratory infection within the past 6 weeks * Presence of other chronic lung diseases (e.g., bronchiectasis, interstitial lung disease, asthma) * Active malignancy * Severe or uncontrolled cardiovascular disease, including recent acute myocardial infarction or malignant arrhythmias * Neurological, orthopedic, or psychiatric conditions that preclude objective functional assessment or participation in exercise training * Use of antioxidant or vitamin supplementation within the past 4 weeks * Determination by a cardiologist that participation in an exercise-based rehabilitation program is not medically appropriate

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD Inflamation Oxidative stress Pulmonary rehabilitation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Istanbul Medeniyet University

    Istanbul, Kadikoy, 34730, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.