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Why are kids hitting puberty earlier? new study aims to find out

NCT ID NCT06263868

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is an observatory that will track up to 3360 children in private healthcare who show signs of early or advanced puberty. Researchers will collect data like height, weight, and pubertal stage to better understand trends and possible causes, such as environmental factors. The goal is to gather reliable information to supplement current knowledge, not to test a treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could provide valuable data to help understand why puberty is starting earlier and guide future research or public health strategies.
What could go wrong
This is an observational study, not a treatment trial. It may not identify clear causes, and data collection might be incomplete or not representative of the general population.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 3,360 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients will be recruited in private heathlcare: 2880 patients distributed between the 2 following groups: PP (Precocious puberty group) and PA (Advanced puberty group), and 480 children in the control group.

Ages

Up to 11 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Precocious puberty group (PP) : * Suspected precocious puberty (girl aged \< 8 years or boy aged \< 9 years when the first signs of development\* appear) * Suspected precocious puberty (girl aged \< 8 years or boy aged \< 9 years when the first signs of development\* appear) Advanced puberty group (AP) : * Suspected advanced puberty (girl aged ≥ 8 and \< 10 years or boy aged ≥ 9 and \< 11 years when the first signs of development\* appear) * First consultation with the investigator (pediatric endocrinologist). Control group : * Boy or girl without signs of pubertal development (Tanner 1); * Matched to the PP group on sex and age (+/- 1 year); * Consultation with the same investigator over the same period (same quarter) as a patient in the PP group Exclusion Criteria: All groups * Consultation with the same investigator over the same period (same quarter) as a patient in the PP group * Family not speaking French, language barrier.

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Conditions

The condition(s) this trial relates to.

precocious puberty

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Puberty, precocious

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    20 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Clinique Saint jean

    ACTIVE_NOT_RECRUITING

    Saint-Jean-de-Védas, 34430, France

  • Clinique du Val d'Ouest

    RECRUITING

    Écully, Auvergne-Rhône-Alpes, 69130, France

  • Clinique du Val d'Ouest

    RECRUITING

    Écully, Auvergne-Rhône-Alpes, 69130, France

  • Clinique du Val d'Ouest

    RECRUITING

    Écully, Auvergne-Rhône-Alpes, 69130, France

  • Clinique rive gauche

    NOT_YET_RECRUITING

    Toulouse, Occitanie, 31300, France

  • Hôpital Femme Mère Enfant, Hospices civils de Lyon

    RECRUITING

    Bron, 69677, France

  • Pediatric Practice

    RECRUITING

    Pessac, New Aquitaine, 33600, France

  • Pediatric practice

    RECRUITING

    Lyon, Auvergne-Rhône-Alpes, 69006, France

  • Pediatric practice

    RECRUITING

    Rennes, Brittany Region, 35200, France

  • Pediatric practice

    RECRUITING

    Chambray-lès-Tours, Centre-Val de Loire, 37170, France

  • Pediatric practice

    RECRUITING

    Essey-lès-Nancy, Grand Est, 54270, France

  • Pediatric practice

    ACTIVE_NOT_RECRUITING

    Levallois-Perret, Hauts-de-Seine, 92300, France

  • Pediatric practice

    RECRUITING

    Fondettes, Indre-et-Loire, 37230, France

  • Pediatric practice

    RECRUITING

    Pau, New Aquitaine, 64000, France

  • Pediatric practice

    NOT_YET_RECRUITING

    Saint-Nazaire, Pays de la Loire Region, 44600, France

  • Pediatric practice

    RECRUITING

    Aix-en-Provence, 13090, France

  • Pediatric practice

    ACTIVE_NOT_RECRUITING

    Marseille, 13008, France

  • Pediatric practice

    RECRUITING

    Marseille, 13012, France

  • Pediatric practice

    RECRUITING

    Nice, 06000, France

  • Pediatric practice

    RECRUITING

    Trélazé, 49800, France

  • Pediatric practice

    RECRUITING

    Paris, Île-de-France Region, 75010, France

  • Pediatric practice

    RECRUITING

    Paris, Île-de-France Region, 75011, France

  • Pediatric practice

    RECRUITING

    Paris, Île-de-France Region, 75017, France

  • Pediatric practice

    ACTIVE_NOT_RECRUITING

    Paris, Île-de-France Region, 75116, France

  • Polyclinique Bordeaux rive droite

    ACTIVE_NOT_RECRUITING

    Lormont, New Aquitaine, 33310, France

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