New hope for Hard-to-Treat cancers: experimental drug PT0511 targets KRAS mutations
NCT ID NCT07300150
First seen Jan 04, 2026 · Last updated May 23, 2026 · Updated 26 times
Summary
This early-phase study tests a new drug called PT0511 in adults with advanced solid tumors that have a KRAS mutation or amplification, including colorectal, pancreatic, and lung cancers. The main goals are to check safety, find the best dose, and see how the drug works alone or with another drug called cetuximab. About 195 participants will take part to help determine if PT0511 can control these difficult-to-treat cancers.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber/Massachusetts General Hospital, Inc
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Email: •••••@•••••
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
Contact Email: •••••@•••••
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New Experimental Therapeutics of San Antonio LLC
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Email: •••••@•••••
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START - South Texas Accelerated Research Therapeutics, LLC
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Email: •••••@•••••
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START Mountain Region
RECRUITINGWest Valley City, Utah, 84119, United States
Contact Email: •••••@•••••
Conditions
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