New drug PT0511 targets tough KRAS cancers in early trial
NCT ID NCT07300150
First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 24 times
Summary
This early-phase study tests a new drug called PT0511 in about 195 adults with advanced solid tumors that have a KRAS mutation or amplification, including colorectal, pancreatic, and lung cancers. The main goals are to check safety, find the best dose, and see how the drug works alone or with cetuximab for colorectal cancer. Participants must have tried at least one prior treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber/Massachusetts General Hospital, Inc
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Email: •••••@•••••
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
Contact Email: •••••@•••••
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New Experimental Therapeutics of San Antonio LLC
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Email: •••••@•••••
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START - South Texas Accelerated Research Therapeutics, LLC
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Email: •••••@•••••
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START Mountain Region
RECRUITINGWest Valley City, Utah, 84119, United States
Contact Email: •••••@•••••
Conditions
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