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Mailed quiz could spot hidden arthritis in psoriasis patients
NCT ID NCT04110522
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether sending a short screening questionnaire directly to people with psoriasis can help detect psoriatic arthritis earlier. 18,000 participants will be randomly assigned to receive the questionnaire or not. Those with high scores will be advised to see a rheumatologist. The goal is to see if this direct-to-patient approach leads to more and earlier diagnoses of psoriatic arthritis.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Psoriasis Epidemiology Screening Tool (PEST) questionnaire
- What this could lead to
- If successful, this approach could help detect psoriatic arthritis earlier in people with psoriasis, potentially leading to faster treatment and better outcomes.
- What could go wrong
- This is a screening study, not a treatment trial. It may not prove that earlier detection improves long-term health, and the questionnaire might miss some cases or cause unnecessary worry.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 18,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2019
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Have an International Classification of Diseases (ICD) code diagnosis of psoriasis but without a confirmed diagnosis of Psoriatic Arthritis prior to study initiation * Be age 18 or older * Be geographically located within a reasonable proximity to the Rheumatology study site Exclusion Criteria: * Have psoriasis and a confirmed diagnosis of psoriatic arthritis made or confirmed by a rheumatologist
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Utah
Salt Lake City, Utah, 84112, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a new pill calm psoriatic arthritis joint pain?
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