Magic mushroom therapy could help Burned-Out doctors find meaning again
NCT ID NCT07565909
First seen May 05, 2026 · Last updated Jun 19, 2026 · Updated 9 times
Summary
This study tests whether a group retreat using psilocybin (the active ingredient in magic mushrooms) can safely help healthcare clinicians who feel depressed and have lost meaning in their work. Seventy-two doctors, nurses, and physician assistants will take part in small groups, receiving preparation, a single psilocybin session, and follow-up integration. The main goals are to check safety and feasibility, and to explore how well the therapy works for easing depression and restoring a sense of fulfillment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
psilocybin
What this could lead to
If successful, this could point toward a new way to help healthcare workers with depression and loss of meaning, using a group retreat format with psilocybin.
What could go wrong
This is an early-phase, single-arm study with no placebo group, so results may not prove effectiveness. Psilocybin can cause temporary anxiety or confusion, and the group format may not suit everyone.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.