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Magic mushroom compound meets mindfulness in new PTSD trial

NCT ID NCT07104916

First seen Mar 05, 2026 · Last updated Jun 18, 2026 · Updated 19 times

Summary

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with mindfulness-based therapy can help ease symptoms of posttraumatic stress disorder (PTSD). About 30 adults with PTSD will receive the drug along with either standard support or extra mindfulness training. Researchers will use brain scans and other tests to see how the treatment affects brain activity and PTSD symptoms over 28 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Ohio State University Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

major depressive disorder post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.