Could a psychedelic drug calm your gut? new trial explores psilocybin for IBS
NCT ID NCT06206265
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 25 times
Summary
This early study tests whether a drug called psilocybin (the active ingredient in magic mushrooms), given alongside talk therapy, can safely reduce symptoms of irritable bowel syndrome (IBS). Fourteen adults with IBS will receive two doses of psilocybin, with some starting right away and others waiting 8 weeks. Researchers will monitor side effects, mood, and changes in pain and stool habits for up to a year.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
Conditions
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