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Blood test may spare some stroke patients unnecessary brain scans

NCT ID NCT05002400

Diagnosis Sponsor: Poitiers University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a blood test measuring PS100B levels could help rule out stroke in patients with symptoms lasting more than 24 hours but less than 4 days. Researchers enrolled 179 patients at a French hospital. If the test proves accurate, it might reduce the need for emergency brain imaging in some cases.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
PS100B blood test
What this could lead to
If successful, this blood test could help doctors quickly rule out stroke in some patients, reducing the need for emergency brain scans.
What could go wrong
This is a small, early study (179 patients) looking at a biomarker that takes hours to rise, so it may not be reliable enough for routine use. The test is not yet proven to replace standard imaging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

179 people

The number who actually took part.

Started

Sep 2021

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients presenting at the Emergency Department of the University Hospital Center of Poitiers for symptoms evocative of stroke for more then 24 hours and less then 4 days, that fit the inclusion and exclusion criteria

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients presenting at the Emergency Department of the University Hospital Center of Poitiers for the following symptoms, which last since more then 24 hours et less then 4 days : * sensitive or motor deficit of one or several limbs * facial paralysis * impairment of speech * dysarthria * vertigo * impairment of vision * oculomotor disorder * diplopia * free patient, without guardianship or curatorship, or subordination * patient not objecting to research Exclusion Criteria: * head trauma that occured less then 15 days ago * known cerebral mass or melanoma * refusal to participate in research * patient benefiting from enhanced protection, namely: minors, persons deprived of their liberty by a judicial or administrative decision, adults under legal protection * pregnant and/or breastfeeding women

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Conditions

The condition(s) this trial relates to.

disease stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

Contacts and locations

Locations

  • C.H.U. de Poitiers

    Poitiers, 86000, France

  • CHU Henri MONDOR

    Créteil, 94000, France

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