Gene therapy trial offers new hope for kidney disease patients
NCT ID NCT07182227
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 29 times
Summary
This study tests a new gene therapy, PS-002, for adults with IgA nephropathy, a kidney disease that can lead to kidney failure. The treatment is given as a single dose and aims to slow or stop the disease. The study includes 32 people who are at high risk of their disease getting worse despite current treatments. Participants will be followed for up to 5 years to check safety and how well the therapy works.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cardiff and Vale University Health Board
NOT_YET_RECRUITINGCardiff, CF14 4XW, United Kingdom
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Leicester General Hospital
NOT_YET_RECRUITINGLeicester, Leicestershire, LE5 4PW, United Kingdom
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Manchester University NHS Foundation Trust
NOT_YET_RECRUITINGManchester, Greater Manchester, M13 9WL, United Kingdom
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Nottingham University Hospitals NHS Trust
RECRUITINGNottingham, Nottinghamshire, NG5 1PB, United Kingdom
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Royal Infirmary of Edinburgh Clinical Research Facility
NOT_YET_RECRUITINGEdinburgh, EH16 4SA, United Kingdom
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Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust
RECRUITINGManchester, Greater Manchester, M13 9WL, United Kingdom
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Southmead Hospital
RECRUITINGBristol, BS10 5NB, United Kingdom
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The Johns Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
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The Royal London Hospital
RECRUITINGLondon, E1 1FR, United Kingdom
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University of Miami Hospital
RECRUITINGMiami, Florida, 33136, United States
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University of Michigan Hospital
NOT_YET_RECRUITINGAnn Arbor, Michigan, 48109, United States
Conditions
Explore the condition pages connected to this study.