Experimental combo for rare Gene-Mutated cancers halted early
NCT ID NCT06682806
First seen Feb 02, 2026 · Last updated May 24, 2026 · Updated 18 times
Summary
This study tested a new drug (PRT3789) combined with the immunotherapy pembrolizumab in people with advanced cancers that have a specific genetic change called SMARCA4. The goal was to see if the combination was safe and could shrink tumors. The study was terminated early after enrolling only 6 participants, so results are limited.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Florida Cancer Specialists
West Palm Beach, Florida, 33401, United States
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Hospital Universitario Fundacion Jimenez Diaz - Servicio de Oncologia
Madrid, 28040, Spain
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IOB - Next Oncology - Hospital Quironsalud Barcelona
Barcelona, 08023, Spain
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John Theurer Cancer Center at Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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SCRI Oncology Partners
Nashville, Tennessee, 37203, United States
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START Barcelona - HM Nou Delfos
Barcelona, 08023, Spain
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Tennessee Oncology, PLLC - Greco-Hainsworth Centers for Research
Nashville, Tennessee, 37203, United States
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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