New hope for rare blood cancers: first human trial of PRT12396 begins
NCT ID NCT07469891
First seen Mar 20, 2026 · Last updated Jun 18, 2026 · Updated 13 times
Summary
This early-stage study tests a new drug, PRT12396, in about 100 people with polycythemia vera or myelofibrosis—rare blood cancers. The main goals are to find a safe dose and check for side effects. Researchers will also look for signs that the drug controls the disease, but this is not a cure and long-term management is expected.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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BRCR Global - Coral Springs
RECRUITINGCoral Springs, Florida, 33065, United States
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Colorado Blood Cancer Institute
RECRUITINGDenver, Colorado, 80218, United States
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START Midwest, LLC
RECRUITINGGrand Rapids, Michigan, 49546, United States
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Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Trials Office
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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Tristar BMT
RECRUITINGNashville, Tennessee, 37203, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.