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Proton therapy under the microscope: is it safer for kids?

NCT ID NCT03223766

First seen Jan 07, 2026 · Last updated Jun 22, 2026 · Updated 28 times

Summary

This study follows 1,000 children with cancer who are receiving proton therapy as part of their treatment at St. Jude Children's Research Hospital. The goal is to track and report any serious side effects caused by the radiation. This is not a treatment trial; instead, it observes what happens when proton therapy is used in real-world care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

proton therapy

What this could lead to

If successful, this study could confirm that proton therapy is a safe option for treating pediatric cancers, potentially reducing long-term side effects compared to standard radiation.

What could go wrong

This is an observational study, not a treatment trial. It only tracks side effects and does not test whether proton therapy works better than other treatments. Results may not apply to all hospitals or patient groups.

Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.