Heavy water study to unlock secrets of aging proteins
NCT ID NCT06269653
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 29 times
Summary
This study aims to measure how quickly proteins are replaced in the body (protein turnover) in healthy adults aged 20 and older. Participants will drink heavy water for 21 days and undergo tests including muscle, skin, and fat biopsies, imaging scans, and strength tests. The goal is to understand how aging affects protein turnover, which could inform future research on age-related diseases.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institute of Aging, Clinical Research Unit
RECRUITINGBaltimore, Maryland, 21224, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
deuterium oxide (heavy water)
What this could lead to
If successful, this study could reveal how aging affects protein turnover in different tissues, potentially guiding future research on age-related health decline.
What could go wrong
This is an observational study with no treatment. It is small (75 people) and only looks at healthy volunteers, so findings may not apply to everyone or lead directly to therapies.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.