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Can Fast-Acting proteins protect muscle after Weight-Loss surgery?

NCT ID NCT01249326

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This study explores how weight-loss surgery changes the body's protein needs and whether fast-absorbing milk proteins can help preserve muscle mass and strength. Researchers will measure nitrogen balance and muscle function in 25 adults with severe obesity before and after gastric bypass or sleeve gastrectomy. The goal is to understand how to best support the body during rapid weight loss and improve recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bariatric surgery (gastric bypass or sleeve gastrectomy) plus fast-absorbing milk protein supplements
What this could lead to
If successful, this could help tailor protein intake after weight-loss surgery to better preserve muscle mass and function, improving recovery and long-term health.
What could go wrong
This is a small, early-stage study with only 25 participants, so results may not apply to everyone. The findings may not lead to clear clinical guidelines, and individual responses to surgery and supplements can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

25 people

The number who actually took part.

Started

Dec 2010

Finished

Mar 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Males and females. * Age between 18 to 60 years. * Body mass index: BMI\> 40 kg/m2, * Biological Review considered satisfactory by the investigator based on the topics covered * Serology HIV ( Human Immunodeficiency Virus )and HCV (Hepatitis C Virus ) negative. * Subject giving his written informed consent * Affiliated to National Health Insurance Exclusion Criteria: * Subject under 18 or over 60 years. * Balance Organic considered abnormal by the investigator. * Serology HIV or HCV positive. * Pregnant or lactating. * For women of childbearing age: β-HCG assay positive and not having reliable contraceptives (oral contraceptive, IUD (Intrauterine Device), implant or hormone patch, abstinence). * Medical or surgical history (judged by investigator to be incompatible with the study). * Subject with unstable psychiatric condition * Blood donation in the two months preceding the study. * Heavy alcohol consumption (\> 2 to 3 glasses per day depending on sex) or presence of an addiction. * Tobacco significant (\> 5 cigarettes / day or equivalent in cigars or pipe tobacco). * Subjects with an allergy or intolerance to dairy products. * Intense sporting activity (\> 5 hours / week). * Being in exclusion on the National Volonteers Data file or having perceived more than 4500 Euros in the year for clinical study participation. * No one under guardianship or not subject to social security. * Subjects deprived of their liberty by judicial or administrative decision. * Refusal to sign the information sheet and written consent for participation * Subject with a cardiovascular or neoplasic evolutive disease * Subject with a severe infection in the 3 months period before inclusion (assessed by doctor during inclusion consultation) * Hypercorticism and dysthyroïdism * Subject with a known neuro-muscular disease * Subject with a chronic or acute inflammatory disease in the 3 months period before inclusion * Subject treated by: corticoids, immunosupressor, anabolic agents, growth factor or having stopped treatment for less than 3 months before inclusion. Furthermore for subjects having undergone a by-pass at Lyon: * Subject consuming pre or probiotics many times per day, having an impact on intestinal flora. * Subject with antibiotics during the 3 months before the beginning of the study. * Subject with an intolerance to dairy products and refusing to consume dairy prod

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France

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