Shorter radiation may be just as good for prostate cancer

NCT ID NCT03367702

Disease control Sponsor: NRG Oncology Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase III trial compares two types of radiation therapy for men with intermediate-risk prostate cancer that hasn't spread. One method, SBRT, delivers high-dose radiation in fewer sessions, while the other, IMRT, uses more standard daily doses. The study tracks side effects and cancer control over time to see which approach is better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: radiation therapy (stereotactic body radiation therapy or intensity-modulated radiation therapy)
What this could lead to: If SBRT works better, it could offer a shorter, more convenient radiation course with fewer side effects for men with prostate cancer.
What could go wrong: This is a large Phase III trial, but results are not yet final. SBRT may not prove superior to standard IMRT, and there is still a risk of side effects or cancer recurrence.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 692 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2018

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Previously untreated (no local therapy such as surgery, radiation cryotherapy, high-intensity focused ultrasound \[HIFU\], etc.) localized adenocarcinoma of the prostate with the following clinical findings: * Clinical stage by digital rectal exam of either T1c or T2a/b (limited to one side of the gland); (American Joint Committee on Cancer \[AJCC\], version 7) or cT1a-c or 2a or 2b * Stages T1a-T1b are eligible if patient underwent transurethral prostatic resection (TURP) * The patient must meet one of the following 3 criteria: 1) Gleason score must be Gleason 7(3+4) with a PSA \< 20 ng/mL, or 2) Gleason 6 (3+3) with a PSA \> 10 ng/mL and \< 20 ng/mL which is considered intermediate risk and eligible for the study (AJCC, version 7), or 3) Group Grade 1 with a PSA \> 10 ng/mL and \< 20 ng/mL or 2 with a PSA \< 20 ng/mL * If patient is receiving a 5-alpha reductase inhibitor at the time of enrollment, the baseline PSA value may be double the initial value and the medication should be discontinued but a washout period is not required; to be eligible, a PSA drawn while still on the medicine must be: * \< 10 ng/mL if Gleason 7(3+4) (note this patient would be on stratification level 1 if PSA \< 5 ng/mL and stratification level 2 if less than 10 ng/mL) * \> 5 ng/mL and less than 10 ng/mL for Gleason 6(3+3) (note this patient would be on stratification level 3) * The prostate volume must be \< 70 cc as reported at time of biopsy or by separate measure with ultrasound or other imaging modalities including magnetic resonance imaging (MRI) or computed tomography (CT) scan * Patients in active surveillance who elect to be treated are eligible if they meet protocol requirements * Age \>= 18 * History and physical including a digital rectal exam 60 days prior to registration * Eastern Cooperative Oncology Group (ECOG) performance status 0-1 60 days prior to registration * MRI of the prostate and pelvis (per institutional standard of care \[SOC\] - should be compliant with PIRADSv2.1 guidelines) within 1 year prior to registration * Bone scan as clinically indicated within 120 days prior to registration * Charlson modified co-morbidity score =\< 4 for patients under 60 and =\< 5 for patients 60 and over 21 days prior to registration * International prostate symptom score (IPSS) of \< 15 21 days prior to registration * The patient must provide study-specific informed consent prior to study entry * Willingness and ability to complete the Expanded Prostate Cancer Index Composite (EPIC-26) questionnaire * Completion of all items of the EPIC-26 which will be data entered at registration 60 days prior to registration * Only English, Spanish, and French-speaking patients are eligible to participate as these are the only languages EPIC-26 has been validated in Exclusion Criteria: * Definitive clinical or radiologic evidence of metastatic disease; no nodal involvement or evidence of metastatic disease allowed as defined by screening of the pelvis * Definitive T3 disease on MRI * Prior or current invasive malignancy with current evidence of active disease within the past 2 years * Exceptions: Non-melanomatous skin cancer, carcinoma in situ of the male breast, penis, oral cavity, or stage Ta of the bladder, or stage I completely resected melanoma * Prior systemic chemotherapy for the study cancer; note that prior chemotherapy for a different cancer is allowable; must be off treatment for at least 3 years * Prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields * The use of hormonal therapy is not allowed; if the patient is on a 5-alpha reductase inhibitor, then they should be stopped prior to treatment once enrolled onto the study; no washout period is required for this study to participate * Severe, active co-morbidity defined as follows: * Human immunodeficiency virus (HIV) positive with CD4 count \< 200 cells/microliter; Note that patients who are HIV positive are eligible, provided they are under treatment with highly active antiretroviral therapy (HAART) and have a CD4 count \>= 200 cells/microliter within 30 days prior to registration; Note also that HIV testing is not required for eligibility for this protocol; this exclusion criterion is necessary because the treatments involved in this protocol may be significantly immunosuppressive * Hepatic insufficiency resulting in clinical jaundice and/or coagulation defects; note, however, that laboratory tests for liver function and coagulation parameters are not required for entry into this protocol; (patients on Coumadin or other blood thinning agents are eligible for this study) * Contraindication to MRI * Cardiac pacemaker or defibrillator * Surgically implanted electrical devices such as spinal stimulation devices or intracranial stimulation devices, cochlear implants, the presence of metallic foreign bodies in the orbits, and incompatible old mechanical heart valves and aneurysm clips

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stage II prostate adenocarcinoma ajcc V7

Contacts and locations

Locations

Adams Cancer Center

Gettysburg, Pennsylvania, 17325, United States
AdventHealth Littleton

Littleton, Colorado, 80122, United States
AdventHealth Parker

Parker, Colorado, 80138, United States
AdventHealth Porter

Denver, Colorado, 80210, United States
Allan Blair Cancer Centre

Regina, Saskatchewan, S4T 7T1, Canada
Alta Bates Summit Medical Center-Herrick Campus

Berkeley, California, 94704, United States
Arizona Center for Cancer Care - Gilbert

Gilbert, Arizona, 85297, United States
Arizona Center for Cancer Care - Scottsdale

Scottsdale, Arizona, 85258, United States
Arizona Center for Cancer Care-Peoria

Peoria, Arizona, 85381, United States
Arizona Center for Cancer Care-Surprise

Surprise, Arizona, 85374, United States
Arizona Oncology Associates-West Orange Grove

Tucson, Arizona, 85704, United States
Arthur J E Child Comprehensive Cancer Centre

Calgary, Alberta, T2N 5G2, Canada
Ascension All Saints Hospital

Racine, Wisconsin, 53405, United States
Ascension Columbia Saint Mary's Hospital - Milwaukee

Milwaukee, Wisconsin, 53211, United States
Ascension Columbia Saint Mary's Hospital Ozaukee

Mequon, Wisconsin, 53097, United States
Ascension Mercy Hospital

Oshkosh, Wisconsin, 54904, United States
Ascension Saint Elizabeth Hospital

Appleton, Wisconsin, 54915, United States
Ascension Saint Francis - Reiman Cancer Center

Franklin, Wisconsin, 53132, United States
Ascension Southeast Wisconsin Hospital - Elmbrook Campus

Brookfield, Wisconsin, 53045, United States
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Asplundh Cancer Pavilion

Willow Grove, Pennsylvania, 19090, United States
Aurora BayCare Medical Center

Green Bay, Wisconsin, 54311, United States
Aurora Medical Center in Summit

Summit, Wisconsin, 53066, United States
Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Beacon Hospital

Dublin, Co Dublin, 18, Ireland
Beebe Health Campus

Rehoboth Beach, Delaware, 19971, United States
Beebe South Coastal Health Campus

Millville, Delaware, 19967, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Bon Secours Cancer Institute at Reynolds Crossing

Richmond, Virginia, 23230, United States
Bon Secours DePaul Medical Center

Norfolk, Virginia, 23505, United States
Boston Medical Center

Boston, Massachusetts, 02118, United States
Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715, United States
Broward Health Medical Center

Fort Lauderdale, Florida, 33316, United States
Broward Health North

Deerfield Beach, Florida, 33064, United States
Bryn Mawr Hospital

Bryn Mawr, Pennsylvania, 19010, United States
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)

Québec, Quebec, G1R 2J6, Canada
CHUM - Centre Hospitalier de l'Universite de Montreal

Montreal, Quebec, H2X 3E4, Canada
CIUSSSEMTL-Hopital Maisonneuve-Rosemont

Montreal, Quebec, H1T 2M4, Canada
Capital Health Medical Center-Hopewell

Pennington, New Jersey, 08534, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carolina Regional Cancer Center

Myrtle Beach, South Carolina, 29577, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Central Maryland Radiation Oncology in Howard County

Columbia, Maryland, 21044, United States
Central Vermont Medical Center/National Life Cancer Treatment

Berlin Corners, Vermont, 05602, United States
Centre De Sante Et De Services Sociaux De Chicoutimi

Chicoutimi, Quebec, G7H 5H6, Canada
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont

Sherbrooke, Quebec, J1H 5N4, Canada
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Christiana Care Health System-Concord Health Center

Chadds Ford, Pennsylvania, 19317, United States
Cleveland Clinic Akron General

Akron, Ohio, 44307, United States
Cleveland Clinic Cancer Center Independence

Independence, Ohio, 44131, United States
Cleveland Clinic Cancer Center Mansfield

Mansfield, Ohio, 44906, United States
Cleveland Clinic Cancer Center/Fairview Hospital

Cleveland, Ohio, 44111, United States
Cleveland Clinic Wooster Family Health and Surgery Center

Wooster, Ohio, 44691, United States
Community Medical Center

Missoula, Montana, 59804, United States
Corewell Health Beaumont Troy Hospital

Troy, Michigan, 48085, United States
Corewell Health Dearborn Hospital

Dearborn, Michigan, 48124, United States
Corewell Health Farmington Hills Hospital

Farmington Hills, Michigan, 48336, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States
Corewell Health William Beaumont University Hospital

Royal Oak, Michigan, 48073, United States
Cross Cancer Institute

Edmonton, Alberta, T6G 1Z2, Canada
Crossroads Cancer Center

Effingham, Illinois, 62401, United States
Dartmouth Cancer Center - North

Saint Johnsbury, Vermont, 05819, United States
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

Lebanon, New Hampshire, 03756, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Deke Slayton Cancer Center

Webster, Texas, 77598, United States
Delaware County Memorial Hospital

Drexel Hill, Pennsylvania, 19026, United States
Drexel Town Square Health Center

Oak Creek, Wisconsin, 53154, United States
Duke Cancer Center Raleigh

Raleigh, North Carolina, 27609, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Durham VA Medical Center

Durham, North Carolina, 27705, United States
East Jefferson General Hospital

Metairie, Louisiana, 70006, United States
Edward Hines Jr VA Hospital

Hines, Illinois, 60141, United States
Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
Exeter Hospital

Exeter, New Hampshire, 03833, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Fox Chase Cancer Center - East Norriton Hospital Outpatient Center

East Norriton, Pennsylvania, 19401, United States
Fox Chase Cancer Center Buckingham

Furlong, Pennsylvania, 18925, United States
Franciscan Health Indianapolis

Indianapolis, Indiana, 46237, United States
Franciscan Health Mooresville

Mooresville, Indiana, 46158, United States
Fresno Cancer Center

Fresno, California, 93720, United States
Froedtert Menomonee Falls Hospital

Menomonee Falls, Wisconsin, 53051, United States
Froedtert West Bend Hospital/Kraemer Cancer Center

West Bend, Wisconsin, 53095, United States
Garnet Health Medical Center

Middletown, New York, 10940, United States
Geauga Hospital

Chardon, Ohio, 44024, United States
Geisinger Cancer Services-Pottsville

Pottsville, Pennsylvania, 17901, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
Geisinger Medical Oncology-Lewisburg

Lewisburg, Pennsylvania, 17837, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Gene Upshaw Memorial Tahoe Forest Cancer Center

Truckee, California, 96161, United States
GenesisCare USA - Key West

Key West, Florida, 33040, United States
GenesisCare USA - Lakewood Ranch

Lakewood Rch, Florida, 34202, United States
GenesisCare USA - Plantation

Plantation, Florida, 33324, United States
Genesys Hurley Cancer Institute

Flint, Michigan, 48503, United States
Grady Health System

Atlanta, Georgia, 30303, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Highland Hospital

Rochester, New York, 14620, United States
Hillcrest Hospital Cancer Center

Mayfield Heights, Ohio, 44124, United States
Intermountain Medical Center

Murray, Utah, 84107, United States
Jefferson Torresdale Hospital

Philadelphia, Pennsylvania, 19114, United States
John Fitzgerald Kennedy Medical Center

Atlantis, Florida, 33462, United States
Juravinski Cancer Centre at Hamilton Health Sciences

Hamilton, Ontario, L8V 5C2, Canada
Kaiser Permanente Cancer Treatment Center

South San Francisco, California, 94080, United States
Kaiser Permanente Dublin

Dublin, California, 94568, United States
Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027, United States
Kaiser Permanente Medical Center - Santa Clara

Santa Clara, California, 95051, United States
Kaiser Permanente Oakland-Broadway

Oakland, California, 94611, United States
Kaiser Permanente-Anaheim

Anaheim, California, 92806, United States
Kaiser Permanente-Rancho Cordova Cancer Center

Rancho Cordova, California, 95670, United States
Kantonsspital Aarau

Aarau, 5001, Switzerland
Karmanos Cancer Institute at McLaren Greater Lansing

Lansing, Michigan, 48910, United States
LSU Healthcare Network / Metairie Multi-Specialty Clinic

Metairie, Louisiana, 70006, United States
Lankenau Medical Center

Wynnewood, Pennsylvania, 19096, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone

New York, New York, 10016, United States
Legacy Good Samaritan Hospital and Medical Center

Portland, Oregon, 97210, United States
Legacy Mount Hood Medical Center

Gresham, Oregon, 97030, United States
Legacy Salmon Creek Hospital

Vancouver, Washington, 98686, United States
Lehigh Valley Hospital-Cedar Crest

Allentown, Pennsylvania, 18103, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405, United States
Lewis and Faye Manderson Cancer Center

Tuscaloosa, Alabama, 35401, United States
Lewistown Hospital

Lewistown, Pennsylvania, 17044, United States
Logan Health Medical Center

Kalispell, Montana, 59901, United States
Logan Regional Hospital

Logan, Utah, 84321, United States
Los Angeles General Medical Center

Los Angeles, California, 90033, United States
Lovelace Radiation Oncology

Albuquerque, New Mexico, 87109, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
Luminis Health Anne Arundel Medical Center

Annapolis, Maryland, 21401, United States
MaineHealth Cancer Care Center of York County

Sanford, Maine, 04073, United States
MaineHealth Coastal Cancer Treatment Center

Bath, Maine, 04530, United States
MaineHealth Maine Medical Center - Portland

Portland, Maine, 04102, United States
MaineHealth Maine Medical Center- Scarborough

Scarborough, Maine, 04074, United States
Marin General Hospital

Greenbrae, California, 94904, United States
Mary Imogene Bassett Hospital

Cooperstown, New York, 13326, United States
Mass General/North Shore Cancer Center

Danvers, Massachusetts, 01923, United States
Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114, United States
McKay-Dee Hospital Center

Ogden, Utah, 84403, United States
McLaren Cancer Institute-Bay City

Bay City, Michigan, 48706, United States
McLaren Cancer Institute-Clarkston

Clarkston, Michigan, 48346, United States
McLaren Cancer Institute-Flint

Flint, Michigan, 48532, United States
McLaren Cancer Institute-Macomb

Mount Clemens, Michigan, 48043, United States
McLaren Cancer Institute-Northern Michigan

Petoskey, Michigan, 49770, United States
McLaren-Port Huron

Port Huron, Michigan, 48060, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Hospital North

Colorado Springs, Colorado, 80920, United States
Memorial Medical Center

Modesto, California, 95355, United States
Mercy Cancer Center - Cape Girardeau

Cape Girardeau, Missouri, 63703, United States
Mercy Cancer Center - Carmichael

Carmichael, California, 95608, United States
Mercy Cancer Center - Elk Grove

Elk Grove, California, 95758, United States
Mercy Cancer Center - Rocklin

Rocklin, California, 95765, United States
Mercy Cancer Center - Sacramento

Sacramento, California, 95816, United States
Mercy Cancer Center-Elyria

Elyria, Ohio, 44035, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Mercy Medical Center - Des Moines

Des Moines, Iowa, 50314, United States
Mercy San Juan Medical Center

Carmichael, California, 95608, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Michigan Healthcare Professionals Clarkston

Clarkston, Michigan, 48346, United States
Michigan Healthcare Professionals Farmington

Farmington Hills, Michigan, 48334, United States
Michigan Healthcare Professionals Macomb

Macomb, Michigan, 48044, United States
Michigan Healthcare Professionals Madison Heights

Madison Heights, Michigan, 48071, United States
Michigan Healthcare Professionals Troy

Troy, Michigan, 48098, United States
Midwestern Regional Medical Center

Zion, Illinois, 60099, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Mobile Infirmary Medical Center

Mobile, Alabama, 36607, United States
Mount Sinai Comprehensive Cancer Center at Aventura

Aventura, Florida, 33180, United States
Mount Sinai Medical Center

Miami Beach, Florida, 33140, United States
New Mexico Oncology Hematology Consultants

Albuquerque, New Mexico, 87109, United States
New York-Presbyterian/Brooklyn Methodist Hospital

Brooklyn, New York, 11215, United States
North Coast Cancer Care

Sandusky, Ohio, 44870, United States
Novant Cancer Institute Radiation Oncology - Supply

Supply, North Carolina, 28462, United States
Novant Health Cancer Institute Radiation Oncology - Wilmington

Wilmington, North Carolina, 28401, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oncology and Hematology Associates of Southwest Virginia

Roanoke, Virginia, 24014, United States
Ottawa Hospital and Cancer Center-General Campus

Ottawa, Ontario, K1H 8L6, Canada
Pamela Youde Nethersole Eastern Hospital

Chai Wan, Hong Kong
Paoli Memorial Hospital

Paoli, Pennsylvania, 19301, United States
Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States
Parkview Hospital Randallia

Fort Wayne, Indiana, 46805, United States
Parkview Regional Medical Center

Fort Wayne, Indiana, 46845, United States
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States
Phelps Health Delbert Day Cancer Institute

Rolla, Missouri, 65401, United States
Piedmont Fayette Hospital

Fayetteville, Georgia, 30214, United States
Piedmont Hospital

Atlanta, Georgia, 30309, United States
Poudre Valley Hospital

Fort Collins, Colorado, 80524, United States
Prisma Health Cancer Institute - Eastside

Greenville, South Carolina, 29615, United States
Prisma Health Cancer Institute - Faris

Greenville, South Carolina, 29605, United States
Prisma Health Cancer Institute - Greer

Greer, South Carolina, 29650, United States
Prisma Health Cancer Institute - Seneca

Seneca, South Carolina, 29672, United States
Prisma Health Cancer Institute - Spartanburg

Boiling Springs, South Carolina, 29316, United States
ProMedica Flower Hospital

Sylvania, Ohio, 43560, United States
Providence Saint Mary Regional Cancer Center

Walla Walla, Washington, 99362, United States
Reading Hospital

West Reading, Pennsylvania, 19611, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Rohnert Park Cancer Center

Rohnert Park, California, 94928, United States
Rush-Copley Medical Center

Aurora, Illinois, 60504, United States
SSM Health Saint Louis University Hospital

St Louis, Missouri, 63104, United States
Saint Agnes Hospital

Baltimore, Maryland, 21229, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Alphonsus Cancer Care Center-Nampa

Nampa, Idaho, 83687, United States
Saint Francis Cancer Center

Greenville, South Carolina, 29607, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint George Regional Medical Center

St. George, Utah, 84770, United States
Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States
Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109, United States
Saint Joseph Hospital - Orange

Orange, California, 92868, United States
Saint Lukes Hospital

Dublin, Co Dublin, 6, Ireland
Saint Peter's Health Partners

Albany, New York, 12208, United States
Salinas Valley Memorial

Salinas, California, 93901, United States
Sands Cancer Center

Canandaigua, New York, 14424, United States
Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501, United States
Sanford Joe Lueken Cancer Center

Bemidji, Minnesota, 56601, United States
Sanford Roger Maris Cancer Center

Fargo, North Dakota, 58122, United States
Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134, United States
Saskatoon Cancer Centre

Saskatoon, Saskatchewan, S7N 4H4, Canada
Scotland Memorial Hospital-Laurinburg Cancer Center

Laurinburg, North Carolina, 28352, United States
Self Regional Healthcare

Greenwood, South Carolina, 29646, United States
Sentara Cancer Institute at Sentara CarePlex Hospital

Hampton, Virginia, 23666, United States
Sentara Norfolk General Hospital

Norfolk, Virginia, 23507, United States
Sentara Obici Hospital

Suffolk, Virginia, 23434, United States
Siteman Cancer Center at Saint Peters Hospital

City of Saint Peters, Missouri, 63376, United States
Siteman Cancer Center at West County Hospital

Creve Coeur, Missouri, 63141, United States
Siteman Cancer Center-South County

St Louis, Missouri, 63129, United States
Smilow Cancer Hospital Care Center - Guilford

Guilford, Connecticut, 06437, United States
Smilow Cancer Hospital Care Center - Waterford

Waterford, Connecticut, 06385, United States
Smilow Cancer Hospital Care Center-Trumbull

Trumbull, Connecticut, 06611, United States
Springfield Memorial Hospital

Springfield, Illinois, 62781, United States
Stanford Cancer Center South Bay

San Jose, California, 95124, United States
Stanford Cancer Institute Palo Alto

Palo Alto, California, 94304, United States
State University of New York Upstate Medical University

Syracuse, New York, 13210, United States
Sutter Medical Center Sacramento

Sacramento, California, 95816, United States
Tata Memorial Hospital

Mumbai, 400 012, India
Temple University Hospital

Philadelphia, Pennsylvania, 19140, United States
Texas Cancer Center

Abilene, Texas, 79606, United States
Texas Oncology Cancer Center Sugar Land

Sugar Land, Texas, 77479, United States
Texas Oncology-McKinney

McKinney, Texas, 75071, United States
Texas Oncology-Plano West

Plano, Texas, 75093, United States
The Christ Hospital

Cincinnati, Ohio, 45219, United States
The James Graham Brown Cancer Center at University of Louisville

Louisville, Kentucky, 40202, United States
The Permanente Medical Group-Roseville Radiation Oncology

Roseville, California, 95678, United States
The Radiation Oncology Center-Hilton Head/Bluffton

Hilton Head Island, South Carolina, 29926, United States
The Research Institute of the McGill University Health Centre (MUHC)

Montreal, Quebec, H3H 2R9, Canada
The Valley Hospital - Luckow Pavilion

Paramus, New Jersey, 07652, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
Thompson Cancer Survival Center

Knoxville, Tennessee, 37916, United States
TidalHealth Peninsula Regional

Salisbury, Maryland, 21801, United States
TidalHealth Richard A Henson Cancer Institute

Ocean Pines, Maryland, 21811, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106, United States
Tulane University School of Medicine

New Orleans, Louisiana, 70112, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92093, United States
UCHealth Memorial Hospital Central

Colorado Springs, Colorado, 80909, United States
UCHealth University of Colorado Hospital

Aurora, Colorado, 80045, United States
UH Seidman Cancer Center at Lake Health Mentor Campus

Mentor, Ohio, 44060, United States
UHHS-Chagrin Highlands Medical Center

Beachwood, Ohio, 44122, United States
UHHS-Westlake Medical Center

Westlake, Ohio, 44145, United States
UM Baltimore Washington Medical Center/Tate Cancer Center

Glen Burnie, Maryland, 21061, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
University Hospitals Portage Medical Center

Ravenna, Ohio, 44266, United States
University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Kansas Cancer Center

Kansas City, Kansas, 66160, United States
University of Kansas Cancer Center-Overland Park

Overland Park, Kansas, 66210, United States
University of Kentucky/Markey Cancer Center

Lexington, Kentucky, 40536, United States
University of Maryland Shore Medical Center at Easton

Easton, Maryland, 21601, United States
University of Maryland/Greenebaum Cancer Center

Baltimore, Maryland, 21201, United States
University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912, United States
University of Michigan Health - West

Wyoming, Michigan, 49519, United States
University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Rochester

Rochester, New York, 14642, United States
University of Vermont Medical Center

Burlington, Vermont, 05401, United States
Utah Valley Regional Medical Center

Provo, Utah, 84604, United States
Valley View Hospital Cancer Center

Glenwood Springs, Colorado, 81601, United States
Vince Lombardi Cancer Clinic - Oshkosh

Oshkosh, Wisconsin, 54904, United States
Vince Lombardi Cancer Clinic-Two Rivers

Two Rivers, Wisconsin, 54241, United States
Virginia Mason Medical Center

Seattle, Washington, 98101, United States
Walter Reed National Military Medical Center

Bethesda, Maryland, 20889-5600, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201, United States
Weisberg Cancer Treatment Center

Farmington Hills, Michigan, 48334, United States
WellSpan Health-York Cancer Center

York, Pennsylvania, 17403, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
West Virginia University Charleston Division

Charleston, West Virginia, 25304, United States
West Virginia University Healthcare

Morgantown, West Virginia, 26506, United States
Woodland Memorial Hospital

Woodland, California, 95695, United States
Yale University

New Haven, Connecticut, 06520, United States
Zablocki Veterans Administration Medical Center

Milwaukee, Wisconsin, 53295, United States

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