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Proton beam therapy aims to cut prostate cancer treatment time and side effects

NCT ID NCT01950351

First seen Jan 05, 2026 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This phase II trial is testing a shorter course of proton beam radiation (hypofractionated) in 241 men with early-stage prostate cancer that hasn't spread. The goal is to see if this precise radiation can kill cancer cells while causing fewer bowel and bladder side effects compared to standard radiation. Researchers are tracking side effects and quality of life over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Proton beam radiation therapy

What this could lead to

If successful, this could offer a more precise, shorter course of radiation for prostate cancer with fewer bowel side effects.

What could go wrong

This is a mid-stage trial with 241 participants, so results are not yet definitive. There is still a risk of side effects, and the approach may not work for all patients.

Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.