Scientists launch largest Real-World study of rare angiosarcoma
NCT ID NCT06375941
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study follows 250 people with localized angiosarcoma, a rare cancer of blood vessels. Researchers will collect information on tumor features, patient history, and standard treatments used in everyday practice. The goal is to better understand the disease and guide future care, but no new treatment is being tested.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If this study succeeds, it could help doctors better understand angiosarcoma and improve future treatment guidelines.
- What could go wrong
- This is an observational study, not a treatment trial. It collects data only, so it won't directly test or provide any new therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 250 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2024
- Expected to finish
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Apr 2034
An estimate. End dates often move.
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
* pathological diagnosis of AS; * any site of origin; * any age; * primary, localized, resectable disease.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * pathological diagnosis of AS; * any site of origin; * any age; * primary, localized, resectable disease. Exclusion Criteria: NA
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
19 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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A.O.U. Careggi
NOT_YET_RECRUITINGFlorence, 50134, Italy
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AOU San Luigi Gonzaga
RECRUITINGOrbassano, Torino, 10043, Italy
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ASL Ospedale San Giovanni Bosco
RECRUITINGTorino, 10154, Italy
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Centro Riferimento Oncologico CRO
RECRUITINGAviano, Pordenone, 33081, Italy
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Fondazione Irccs San Gerardo Dei Tintori
NOT_YET_RECRUITINGMonza, 20900, Italy
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Fondazione Policlinico Campus Biomedico
RECRUITINGRoma, 00128, Italy
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IOV Istituto Oncologico Veneto IRCCS
RECRUITINGPadova, 35128, Italy
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IRCCS Istituti Fisioterapici Ospitalieri
NOT_YET_RECRUITINGRoma, 00144, Italy
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IRCCS Istituto Europeo di Oncologia
NOT_YET_RECRUITINGMilan, 20141, Italy
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IRCCS Istituto Nazionale Tumori - Milano
RECRUITINGMilan, 20133, Italy
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Istituto Clinico Humanitas Research Hospital IRCCS
NOT_YET_RECRUITINGRozzano, Milano, 20089, Italy
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Istituto Nazionale Tumori_Fondazione "G.Pascale"
RECRUITINGNaples, 80131, Italy
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Istituto Ortopedico Rizzoli IOR
RECRUITINGBologna, 40136, Italy
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Istituto Tumori "Giovanni Paolo II" I.R.C.C.S.
NOT_YET_RECRUITINGBari, 70124, Italy
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Nuovo Ospedale di Prato - S. Stefano
RECRUITINGPrato, 59100, Italy
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Ospedale Policlinico san Martino IRCCS
RECRUITINGGenova, 16132, Italy
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Ospedale di Trento
NOT_YET_RECRUITINGTrento, 38123, Italy
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Policlinico "Paolo Giaccone"
RECRUITINGPalermo, 90127, Italy
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Policlinico "Sant'Orsola-Malpighi"
RECRUITINGBologna, 40138, Italy
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Other studies related to the condition(s) this trial covers.
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- New combo therapy aims to shrink sarcomas
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- New cocktail aims to shrink sarcomas: bevacizumab joins chemo in phase 2 trial
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- New hope for rare cancers? drug combo shows promise in early trial