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Which anesthesia is safer for brain aneurysm repair? new study investigates

NCT ID NCT07542015

Knowledge-focused Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two types of anesthesia—propofol alone versus a mix of propofol and ketamine—in 46 adults having elective surgery for unruptured brain aneurysms. Researchers measured the diameter of the optic nerve sheath (a marker of brain pressure) at several points during surgery. The goal was to see which anesthesia method better controls brain pressure and maintains stable vital signs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Propofol and Ketamine
What this could lead to
If successful, this could help doctors choose the safest anesthesia for brain aneurysm procedures to better manage brain pressure.
What could go wrong
This is a small, completed study with only 46 participants, so results may not apply to all patients. It measures a surrogate marker, not direct patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

46 people

The number who actually took part.

Started

Jun 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients aged 18-75 years with unruptured intracranial aneurysms scheduled for elective endovascular treatment under general anesthesia at Ankara City Hospital Bilkent.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 75 years * Patients scheduled for elective endovascular treatment of unruptured intracranial aneurysms * ASA physical status I-III * Glasgow Coma Scale score of 15 * Ability to read and write and provide written informed consent Exclusion Criteria: * Age under 18 or over 75 years * ASA physical status IV or higher * History of ocular disease or previous eye surgery * Presence of giant aneurysm * Increased intracranial pressure * Coronary artery disease * Psychiatric or neurological disorders interfering with consent or assessment * Emergency surgical indication

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Conditions

The condition(s) this trial relates to.

brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral aneurysm unruptured Cerebral aneurysms Unruptured intracranial aneurysm

Contacts and locations

Locations

  • Ankara City Hospital Bilkent

    Ankara, 06800, Turkey (Türkiye)

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