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Face-Down donors could boost lung transplants

NCT ID NCT07251777

Knowledge-focused Sponsor: Hospital de Alta Complejidad del Bicentenario Esteban Echeverría Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether placing brain-dead organ donors on their stomach (prone position) helps keep their lungs healthy enough for transplant. Researchers compared this to the usual back-lying (supine) position in 254 donors across 10 hospitals in Argentina. The goal was to see if prone positioning increases the number of lungs that can be used for transplantation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

254 people

The number who actually took part.

Started

Jun 2023

Finished

May 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who died under neurological criteria * 18 to 70 years of age * Meet multi-organ donor criteria * That they have no opposition to the donation. Exclusion Criteria: * Patients who have expressly stated that they do not donate organs * Patients who, for some reason, cannot establish a prone position * Deceased with contraindication for organ donation. Elimination criteria * Time between diagnosis of ME and prone greater than 12 hours * Loss of more than 20% of data on main variables. * Require changing a patient from the prone to the supine position for any reason

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Conditions

The condition(s) this trial relates to.

Brain Death

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DONORS Lung procurement Lung transplantation Prone position Tissue donors

Contacts and locations

Locations

  • Hospital de Alta Complejidad del Bicentenario Esteban Echeverría

    Monte Grande, Buenos Aires, 1842, Argentina

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