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New therapy combo aims to keep women in opioid recovery longer

NCT ID NCT07115030

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 30 times

Summary

This study tests a new stepped care program called PCT+2HOPE for women with opioid use disorder who have also experienced intimate partner violence and have PTSD symptoms. The program combines group therapy with optional individual sessions to address trauma and improve recovery. Researchers will compare this approach to standard care in 532 women to see if it helps them stay in medication-based treatment for opioid use disorder longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Community Health Resources (CHR) Pathways Opiate Treatment Program

    NOT_YET_RECRUITING

    Enfield, Connecticut, 06082, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Liberation Programs

    RECRUITING

    Bridgeport, Connecticut, 06610, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The APT Foundation, Inc.

    NOT_YET_RECRUITING

    West Haven, Connecticut, 06516, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

behavioral intervention (Present-Centered Therapy and Helping to Overcome PTSD through Empowerment)

What this could lead to

If successful, this could provide a more effective way to keep women in opioid use disorder treatment by addressing trauma and PTSD alongside addiction.

What could go wrong

This is a behavioral study, not a drug trial, so results may vary based on individual participation and site implementation. The study is still recruiting and outcomes are measured at 26 weeks, so long-term effects are unknown.

Conditions

The condition(s) this trial relates to.

combat disorder opiate dependence post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.