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New score could help decide when third chemo is worth it for breast cancer

NCT ID NCT01574170

First seen Apr 24, 2026 · Last updated Jun 22, 2026 · Updated 11 times

Summary

This study aims to create a score that helps doctors identify which patients with metastatic breast cancer are likely to live longer with a third line of chemotherapy. Researchers will collect clinical, histological, and biological data from 267 women starting third-line treatment. The score will be tested in a second group of patients to see if it reliably predicts survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • C.M.C.O. Claude Bernard

    Albi, 81000, France

  • CHRU Brest

    Brest, 26609, France

  • CHU Jean Minjoz

    Besançon, 25030, France

  • CHU Rangueil

    Toulouse, 31000, France

  • Centre Eugène Marquis

    Rennes, 35042, France

  • Centre Georges François Leclerc

    Dijon, 21079, France

  • Centre Hospitalier Intercommunal de Castres-Mazamet

    Castres, 81108, France

  • Centre Hospitalier Jean Rougier

    Cahors, 46005, France

  • Centre Hospitalier de Rodez

    Rodez, 12000, France

  • Centre Paul Strauss

    Strasbourg, 67065, France

  • Centre d'Oncologie et de Radiothérapie du Parc

    Dijon, 21000, France

  • Clinique La Croix du Sud

    Quint-Fonsegrives, 31130, France

  • Institut Claudius Regaud

    Toulouse, 31052, France

  • Institut de Cancérologie de Lorraine

    Vandœuvre-lès-Nancy, 54519, France

  • Institut de Cancérologie de l'Ouest Paul Papin

    Angers, 49933, France

  • Polyclinique de l'Ormeau

    Tarbes, 65000, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors identify which patients with metastatic breast cancer are most likely to benefit from a third round of chemotherapy, avoiding unnecessary treatment for others.

What could go wrong

This is an observational tool, not a treatment. The score needs validation and may not improve survival or quality of life directly. Results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

breast carcinoma breast neoplasm metastatic malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.