Probiotic study for diabetes and COPD halted early
NCT ID NCT05492448
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether taking probiotics alongside regular treatment could help lower blood sugar and improve lung function in people with both type 2 diabetes and chronic obstructive pulmonary disease (COPD). The trial planned to enroll 30 adults aged 50-85, but it was terminated early. Researchers measured changes in blood sugar levels and lung capacity over 12 weeks.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Sep 2022
- Finished
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Dec 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subjects are between 50-85 years old, and clinical diagnosis of T2DM (HbA1c ≥ 6.5% or fasting plasma glucose ≥ 126 mg/dL or oral glucose tolerance test 2-hour plasma glucose ≥ 200 mg/dL). * Patients with stable pulmonary obstruction (pulmonary function FEV1/FVC \<0.7) with symptoms of pulmonary obstruction. * Subjects can cooperate with the collection of experimental specimens and return for regular visits. * The patient or family members have signed the informed consent form. * The patient must receive adjuvant treatment with probiotic for 12 weeks. Exclusion Criteria: * The patient or caregiver is unable to follow the physician's instructions for the trial, including the completed symptom assessment form and compliance with medication. * The patient has a history of related allergic reactions, or the use of other highly sensitive or contraindicated drugs (Allergy to antibiotics or antipyretics). * The patient have taken oral immunosuppressive drugs, intravenous steroids or T cell inhibitor ointments within the past 2 weeks. * The patient has consumed probiotic-related products (including drops, lozenges, capsules, powder and yogurt) within the past 1 month. * The patient received high doses of steroids within the past 1 month. * The patient with active infection or severe pulmonary disease (eg, tuberculosis, bronchiectasis, or fibrosis). * The patient is receiving treatment for a major disease or congenital disease. * The patient is not suitable to participate in the trial as assessed by the professional physician.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Glac Biotech Co., Ltd.
Tainan, 74442, Taiwan
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