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Gut bacteria may tame chemo inflammation in breast cancer

NCT ID NCT07607548

Symptom relief Sponsor: Poznan University of Medical Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking a daily probiotic supplement could reduce inflammation caused by chemotherapy or immunotherapy in women with breast cancer. Sixty women took either a probiotic or a placebo for eight weeks while receiving treatment. Researchers measured changes in blood markers of inflammation to see if the probiotic helped.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Probiotic (Lactiplantibacillus plantarum 299v)
What this could lead to
If it works, this could point toward a simple way to reduce harmful inflammation during breast cancer treatment, potentially improving outcomes.
What could go wrong
This is a small, early-stage study focused on blood markers, not on whether cancer comes back. The results may not lead to a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Oct 2022

Finished

Apr 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * first-time chemotherapy * written consent to participate in the research * no antibiotic and probiotic therapy in the last 3 months Exclusion Criteria: * serious comorbidities (chronic renal failure, diabetes, autoimmune diseasese, unstable coronary artery disease or other cancers) * previous history of cancer * smoking cigarettes or using other stimulants * another probiotic supplementation * qualification for another type of treatment - surgery or hormone therapy

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Probiotic therapy

Contacts and locations

Locations

  • Greater Poland Cancer Centre

    Poznan, 61-866, Poland

More trials for these conditions

Other studies related to the condition(s) this trial covers.