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Can good bacteria beat bladder infections? new study investigates

NCT ID NCT05895578

Disease control Sponsor: ProbiSearch SL Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study tests whether taking a probiotic (a 'good' bacteria) can help women who get frequent urinary tract infections (UTIs). About 90 women with a history of repeat UTIs will take either a probiotic or a placebo (a dummy pill) for 6 months. The goal is to see if the probiotic reduces the number of infections and changes the bacteria in the urinary tract.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2023

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult women with aged between 18 and 65 years old, diagnosed with recurrent UTI (defined as at least two episodes during the last six months or three during the last 12 months). * Diagnosed, the last 7days, for a new UTI episode. * Written informed consent signed. Exclusion Criteria: * Pregnant, breastfeeding or planning to become pregnant during the study. * Congenital abnormalities of the urinary tract. * Renal functional alterations, such as neurogenic bladder or vesicoureteral reflux. * Relevant renal disorders, such as interstitial cystitis, renal lithiasis, renal failure, kidney transplantation, pyelonephritis, renal nephropathy, etc. * Permanent catheter. * Immunocompromised (eg: cancer and/or transplant, patients who are taking immunosuppressive drugs, patients with hereditary diseases that affect or may affect the immune system). * Type I diabetes. * With a defect in the intestinal epithelium barrier (eg: chronic diarrhea, inflammatory bowel disease). * Heart failure and cardiac medical history (eg, artificial heart valve, medical history of infective endocarditis, rheumatic fever, or cardiac malformation). * Under antibiotics prophylactic treatment without willingness to leave it at the time of inclusion. * Probiotics supplementation during the previous 2 weeks. * To have received Urovac, Uro-Vaxom or equivalent vaccine during the last year. * Currently participating in another clinical trial.

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Conditions

The condition(s) this trial relates to.

bacterial urinary tract infection urinary tract infection urinary tract infections, recurrent, susceptibility to

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Recurrent urinary tract infection

Contacts and locations

Locations

  • Hospital La Moraleja

    Madrid, Spain

  • Hospital La Zarzuela

    Madrid, Spain

  • Hospital San Francisco de Asís

    Madrid, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.