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Tailored talk therapy shows promise for Non-Verbal kids with autism

NCT ID NCT03883139

Symptom relief Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This study tests whether personalized sequences of behavioral interventions can help minimally verbal preschoolers with autism improve their language skills. Researchers will compare two teaching approaches—JASPER (play-based) and DTT (structured)—to see which works best for each child. The goal is to reduce the number of children who remain minimally verbal by age 6.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
behavioral interventions (JASPER and DTT)
What this could lead to
If successful, this could provide a tailored approach to help minimally verbal children with autism improve their communication skills, potentially reducing the number of children who remain minimally verbal by age 6.
What could go wrong
This is a relatively small, early-stage study (140 children) testing behavioral therapies, not a drug or cure. Results may not apply to all children with autism, and improvements may be modest or vary widely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

140 people

The number who actually took part.

Started

Mar 2021

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

36 to 59 months

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * children meeting ADOS-2 criteria for ASD, * age 36-59 months * who have had \> 3 months early intervention/preschool (to ensure that children already have been exposed to some community interventions) and * use \< 20 functional words (i.e., non-echoed, non-scripted). Additional inclusion criteria are: * stable medication over the past 6 months, and * nonverbal mental age of \>12 months on the Mullen Scales of Early Learning (visual reception and fine motor subscales). Exclusion Criteria: * We will exclude children who have sensory and motor impairments (e.g., visual impairment, deaf or hard of hearing) and with known genetic syndromes (e.g., Down Syndrome). * We will not exclude on the basis of AAC exposure, but expect few will be exposed at these ages.

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Conditions

The condition(s) this trial relates to.

autism autism spectrum disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Autism spectrum disorder

Contacts and locations

Locations

  • UCLA

    Los Angeles, California, 90095, United States

  • University of Oregon

    Eugene, Oregon, 97403, United States

  • University of Rochester

    Rochester, New York, 14642, United States

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