Can special goggles reduce CRPS pain? new study tests prism therapy
NCT ID NCT07370012
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether wearing prism goggles during pointing exercises can reduce pain in people with Complex Regional Pain Syndrome (CRPS) type I. Fifty-four patients with CRPS after a wrist fracture or surgery were split into two groups: one used real prism goggles, the other used sham goggles. Both groups also received standard physical therapy. The goal was to see if prism adaptation therapy could lower pain intensity and improve other symptoms like joint movement.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- prism adaptation therapy using prismatic-lens goggles
- What this could lead to
- If it works, this could offer a simple, non-drug way to ease pain and improve movement for people with CRPS.
- What could go wrong
- This is a small, early study with only 54 participants. The results may not apply to everyone, and the therapy might not work better than a sham treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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54 people
The number who actually took part.
- Started
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Oct 2023
- Finished
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May 2024
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Individuals aged between 18 and 75 years * Patients diagnosed with CRPS Type 1 according to the IASP 2003 CRPS Budapest diagnostic criteria * Presence of traumatic etiologies, including surgical procedures, fractures, or immobilization * Patients who consented to participate and provided written informed consent Exclusion Criteria * History of inflammatory, autoimmune, hematologic, or neoplastic diseases * Diabetes mellitus, thyroid disorders, hepatic or renal failure * History of cranial trauma or cranial surgery within the preceding 6 months * Use of diuretics, anti-inflammatory, antineoplastic, corticosteroid, immunosuppressive, antidepressant, or anxiolytic medications within the past 2 months * Use of anticholinergic medications within the past 7 days * Active ocular infection, inflammation, allergy, or recent use/exposure to ophthalmic drops * History of lens or ocular surgery within the last 3 months * Current or previous use of glasses or contact lenses, or diagnosis of refractive error ≥0.5 diopters * Peripheral nerve injury in the affected hand consistent with CRPS Type 2 as per Budapest criteria * Known progressive or non-progressive peripheral or central nervous system disorders * CRPS Type 1 developing subsequent to central nervous system injury (e.g., stroke) * Patients in the acute phase following primary or secondary tendon repair * Presence of comorbid conditions likely to impair functionality and health-related quality of life, such as decompensated heart failure, chronic kidney failure, or malignancy * Comorbid diseases affecting hand function, including rheumatoid arthritis, psoriatic arthritis, or other inflammatory disorders involving the hand * Joint restriction and/or muscle weakness in the affected extremity that would impede movement * History of acute upper-extremity deep vein thrombosis or arterial thrombosis * Arterial or venous injury and/or history of arterial or venous repair surgery * History of heavy alcohol consumption or inappropriate opioid use * Inadequately treated psychiatric disorders or conditions, such as major depression, anxiety, or schizophrenia * Recurrent diagnosis of CRPS Type 1, defined as patients experiencing repeated episodes
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ankara Etlik City Hospital
Ankara, Ankara, 06170, Turkey (Türkiye)
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