Immunotherapy-Chemo cocktail aims to wipe out penile cancer before surgery

NCT ID NCT06353906

Recruiting now Disease control Sponsor: The Netherlands Cancer Institute Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 30 times

Summary

This study tests whether giving a combination of chemotherapy (carboplatin/paclitaxel) and an immunotherapy drug (pembrolizumab) before surgery can completely eliminate cancer in men with advanced penile cancer that has spread to lymph nodes. About 27 participants will receive the treatment, and researchers will check if the cancer is gone after surgery. The goal is to improve outcomes for this rare and serious cancer.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

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Locations

NKI-AVL
RECRUITING

Amsterdam, North Holland, 1066CX, Netherlands

Contact Phone: •••-•••-•••• Email: •••••@•••••
UZ Leuven
RECRUITING

Leuven, 3000, Belgium

Contact

Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED PENILE CARCINOMA MALE UROGENITAL DISEASES MALE UROGENITAL DISEASES PENILE CANCER PENILE SQUAMOUS CELL CARCINOMA UROGENITAL NEOPLASMS UROLOGIC NEOPLASMS UROLOGIC NEOPLASMS