Your own blood may help your gums heal faster after a tooth pull
NCT ID NCT07595198
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding Platelet-Rich Fibrin (PRF) – a natural substance made from your own blood – to a bone graft helps the extraction site heal faster and grow more bone. Fourteen adults needing two tooth extractions will receive PRF plus bone graft in one socket and standard bone graft with a collagen membrane in the other. The study lasts about 4 months and compares gum closure, pain, bone changes, and new bone growth between the two treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Platelet-rich fibrin (PRF) made from your own blood, combined with bone graft
- What this could lead to
- If it works, this could lead to faster healing and better bone growth after tooth extraction, reducing the need for additional procedures before dental implants.
- What could go wrong
- This is a very small early study with only 14 people, so results may not apply to everyone. There is also a risk of bruising or discomfort from the blood draw.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 14 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients of age between 18-80. 2. Non-smokers or former smokers with at least a 5-year successful cessation history. 3. Patients with normal systemic health (ASA-I) or well-controlled/stable systemic conditions (ASA-II), such as diabetes with HbA1c \< 7.0%, no recent acute myocardial infarction and cerebrovascular accidents within 6 months, or any contraindication for periodontal or implant surgery. 4. Patients treatment planned for extraction and ridge preservation for at least 2 non-adjacent single-rooted teeth. Exclusion Criteria: 1. Current smokers, smokers who have quit \<5 years prior to study entry. 2. Pregnant or lactating women 3. Patients with substance or alcohol abuse 4. Patients with a history of antiresorptive therapy, head and neck radiotherapy, and chemotherapy for malignant tumors 5. Other systemic conditions or medications affecting wound healing. 6. Poor plaque control with plaque score \> 20% 7. Active/untreated odontogenic and periodontal infections
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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